Microanatomy. The bladder wall itself is smooth muscle. The inner side of the bladder is lined with a mucosal membrane consisting of a surface glycocalyx that protects the cells beneath it from urine, the urothelium (a form of transitional epithelium ), a basement membrane, and the lamina propria. Jul 07, 2014Of the 3 donor organs, the ECM derived from urinary bladder was the only intact basement membrane complex that survived processing and modulated in vivo growth patterns. Cellular and molecular research conducted by Badylak et al 6 demonstrated that ECM scaffolds derived from xenogenic UBM provide a biocompatible material that allows inductive tissue remodeling and wound. A thin basement membrane separates the urothelium from the underlying lamina propria. The latter is formed of abundant connective tissue containing a rich vascular network, lymphatic channels, sensory nerve endings, and a few elastic fibers. The lamina propria varies in thickness in the empty versus the distended bladder but is generally thinner in the areas Urinary Bladder Material (UBM) that contains a relatively intact Basement Membrane along with other components associated with Extracellular Matrix (ECM). This Basement MembraneECM Wound Matrix is a naturally resorbable acellular biomaterial. The unique characteristic of the How can the answer be improved. Mucous membrane (mucosa) Transitional epithelium; lines the bladder, ureters, and urethra Epithelial layer Contains no blood or lymphatic vessels Basement membrane Lies beneath the epithelial layer; single layer of cells separating the epithelial layer from the lamina propria; a. Anatomy of the Urinary Bladder. The urinary bladder leis within the pelvic cavity. The bladder lies behind the symphysis pubis. It is below the parietal peritoneum. Urine produced in the kidneys flows into the bladder via the ureters. The urine is ultimately excreted from the bladder through the urethra. Order as fluid flows from the filtration membrane through the nephron. 1, 5, 3, 4, 2 Renal Corpuscle, proximal tube, loop of Heinle, distal tube, collecting duct the capillary epithelium, basement membrane, and podocytes form the. The triangular area of the urinary bladder between the two ureters posteriorly and the. BLADDER, RENAL PELVIS, and URETERS The mucosa of the urinary tract consists of: The EPITHELIAL LAYER contains no blood vessels or lymphatics. The BASEMENT MEMBRANE, a sheet of extracellular material, functions as a filtration barrier and a boundary involved in generating and maintaining tissue structure. To test urinary bladder matrix (UBM) as a potential treatment for tympanic membrane (TM) healing and regeneration. Study Design This prospective pilot study was designed to provide both qualitative and semiquantitative assessment of temporal and spatial healing events in the chinchilla model of chronic TM perforations with and without UBM patching.